Sunday, October 6, 2019
Potential reviews on peer-reviewed journal articles related to the Literature review
Potential reviews on peer-reviewed journal articles related to the dimension of international entrepreneurship - Literature review Example However international entrepreneurial efforts to gain hold of significant opportunities are disturbed by certain factors limiting accessibility of the international entrepreneur to such opportunity zones. The paper relating to the above fact tends to reflect on the importance of opportunities and how the paradigm of accessibility enhances the value addition to the opportunity exploration activities of the international entrepreneur. International Entrepreneurship Baker, Gedajlovic and Lubatkin (2005) and Giamartino, McDougall and Bird (1993) observe that the concept of international entrepreneurship gains potential in the amalgamation of two distinct sets of studies relating to the domain of ââ¬ËInternational Businessââ¬â¢ and ââ¬ËBusiness Entrepreneurshipââ¬â¢. The main focus of the International Entrepreneur like the Regional or Local Entrepreneur lies in investigating, evaluating and thereby optimally exploiting the emergence of new opportunities in the global landscap e. The international entrepreneur having gained sight of new opportunities relating to the specific or diversified business domain in the international arena tends to evaluate the accessibility parameters to the same. Thus business decisions are framed not only in terms of the opportunities sighted but also in the process of gaining optimal benefits related to such. Henceforth a successful entrepreneur not only endeavours to locate significant opportunities but also tries to evaluate the institutional and infrastructural support pertaining to the different international regions (Baker, Gedajlovic and Lubatkin, 2005, p.492, 496; Giamartino, McDougall and Bird, 1993, p.39). Plattner (2005) and Peterson (1988) remarks that the dimension of international entrepreneurship gains dominance in the light of globalisation. The emergence of globalization has led to the growth of enhanced cooperation pertaining to transnational boundaries thereby helping in the mutual growth of different nation s. No nation in this globalized climate tends to operate in an isolated mode. Thus solutions to entrepreneurial and other issues are sought from amongst the cooperation and support rendered in terms of infrastructures, policies and opportunities by other global nations that work to form a mutual association like Commonwealth Nations (Plattner, 2005, p.510; Peterson, 1988, p.7). Probing for International Opportunities Czinkota et al (2011) highlights that international companies to become successful in the globalised scale are required to conduct an effective probe to the level of changes occurring in the external environment pertaining to different international regions. The international entrepreneurs to succeed in the highly competitive and changing global business environment are required to understand the pattern and level of alterations happening and thereby effectively adapt to such changes. Organisational managers are thus required to reorganise and restructure the business c oncerns to gain ease of access to potential opportunities and resources in the international business arena (Czinkota et al, 2011, p.25). The international entrepreneur in terms of Czinkota et al (2011) and Secor (2007) is not required to evaluate the characteristics or features of diverse international zones ranging across different geographies in a separate fashion. Rather the entrepreneur
Saturday, October 5, 2019
Needs of people with disabilities in Health and Social Care Assignment
Needs of people with disabilities in Health and Social Care - Assignment Example The principal test folks of youngsters with ASD face are the conclusion itself, which can bring disaster, nervousness, annoyance and an inclination that life has been uncalled for, as stated by Webmd. "You don't need to child yourself about how hard it is," said Robert A. Naseef, Ph.d., a clinical clinician in Philadelphia, the writer of the book "Uncommon Children, Challenged Parents," and the father of a become child with extreme Autism. As he educated Webmd, "The great thing concerning getting a conclusion is that then you get a heading in what will help your youngster. More often than not, when children get the right help and begin making advancement, their guardian's state of mind lights up and you have some trust once more." Ã An alternate obstacle for folks is the strain having a youngster with such far reaching needs puts on the family unit. Naseef noted to Webmd that pressure can enter relational unions on the grounds that managing a mental imbalance is so expending and he urges couples to attempt to set aside a few minutes for their marriage. One proposal he has is having an "in-home" night out, so that folks don't need to stress over getting a sitter, and appreciating a calm supper and film after the children have gone to bunk. An alternate trouble for families might be the way kin feel dominated by the needs of the youngster with extreme Autism, keeping in mind some have the capacity to structure a nearby relationship, others may lament the passing of a commonplace mate.
Friday, October 4, 2019
Suffering from depression Essay Example for Free
Suffering from depression Essay In one of the first workshops we initially produced a brainstorm of ideas as to why people may be institutionalised. Below I have listed a selection of illnesses which were brainstormed.à Medication non-compliance: Not following treatment and/or not taking medications as prescribed.à Cognitive impairment: Defined as unusually poor mental function, associated with confusion, forgetfulness and difficultyà Depression: A psychiatric disorder showing symptoms such as persistent feelings of hopelessness, dejection, poor concentration, lack of energy, inability to sleep, and, sometimes, suicidal tendencies Incontinence: Often used to refer to a lacking in moderation or self-control, especially related to sexual desire. à Everyone worked in pairs where one of us had been put into the institution by the other. Holly and I worked together, we decided I would be the character in the institution and I was then hot-seated. I decided I was a thirty-five year old woman who had been left by her husband and as a result of this, tragically suffering from depression. As a pose to helping me herself, Holly carelessly decided it was best to leave me in an institution, not knowing this sudden change in surroundings, faces and routine would in fact provoke my illness, leaving me worse than before. When brainstorming ideas as to why people may be institutionalised, depression seemed an obvious and popular idea. This influenced my reasons for rendering my character depressed. After we were hot-seated our teacher asked us questions about the characters we had created, I found the hot-seating helped tremendously when trying to understand and form my character, thus making it easier to answer questions about her. As I was able to understand my character through the hot-seating, I found I was able to form a deeper connection with her; I believed this would significantly help my portrayal when acting her character. We then created a duologue. This helped me further develop my character as it allowed me to see how she reacted when left face-to-face with Holly, through improvisation. It was clear from our characters opposing behavior towards one another that our relationship had been damaged due to the institution. Not only had my condition worsened but Hollys cold nature penetrated the already bad atmosphere between us making everything more awkward.Holly visits the institution to see if my condition has improved. This is the first time in two years she has visited and my hostile behavior towards her shows I am affected by her lack of visits. When she enters my room I am sitting in the corner, dribbling, rocking and the lights are off; she is horrified my depression has worsened and tries to leave immediately. Quickly I get up and run to the door, barricading it. I ask her why she put me here and left me for two years, followed by my monologue. In reply to this Holly performs her monologue explaining my depression was affecting her and everyone around me. Furiously, Holly pushes me aside and runs out of door, I am left crying on the floor in a ball, screaming and shouting why did you do this to me, scene cuts here. FINAL PERFORMANCE I found the final performance ran successfully, Holly and I remembered our lines and our stage directions; this, I thought, played a big part in the overall success of our performance. I believe my character came across well to the audience as the general feedback was positive- this showed the audience was able to identify with and understand my characters feelings and difficulties. Although the majority of the performance went well I, however, believe there is always room for improvement. Holly and I could have incorporated a flash back at the beginning of the scene, showing the audience the day I was put into the institution. I think this may have furthered the audiences understanding of my character and make the fact my condition had not improved clearer. This would not have only benefited the audience, but myself. By developing the scene in this way, I would have been able to also develop my character further on a whole, learning more about her.
Thursday, October 3, 2019
Respiratory Infections Caused By Bacteria Biology Essay
Respiratory Infections Caused By Bacteria Biology Essay -Respiratory infections caused by bacteria are quite so many. They can be differentiated by placing them into where they actually cause disease in the respiratory system or tract. Some bacteria cause disease in the upper respiratory tract whilst others affect the lower respiratory tract. The upper respiratory tract comprises the nasal cavity, pharynx and the larynx, whilst the lower respiratory tract is made up of the trachea, primary bronchi and the lungs. When it comes to aetiology, the respiratory infections caused by bacteria can be compared and contrasted as follows: Legionnaires disease is caused by the bacteria Legionalla pneumophila, which is a rod shaped, motile and gram negative, fastidious bacteria. Legionnaires disease is one of the most common causes of atypical pneumonia in hospitalized patients. It is the second most common cause of community-acquired bacterial pneumonia and travel-acquired pneumonia.Legionelloses can occur both sporadically and in epidemics. And over the past decade, Legionnaires Disease cases have increased. This is so because of the common use of central air conditioning, especially in office hotels, buildings and hospitals. In contrast to Legionalla pneumophila, Haemophilus influenzae is a nonmotile, but is also a fastidious, Gram-negative, rod-shaped bacterium like L. pneumophila. Non capsular type b H. influenzae causes is associated with acute exacerbations of chronic bronchitis. Disease is e much more common in children than older age groups.. Haemophilus influenzae can cause infection in the respiratory tract, which can spread to other organs. Many species of Haemophilus are normal residents in the upper airways of children and adults and rarely cause disease. Usually, Haemophilus influenzae can cause infections in children and sometimes in adults who have a chronic lung disorder or a weakened immune system. Diphtheria, which is an acute infectious bacterial disease primarily involving the mucous membrane of the upper respiratory tract (nose, tonsils, pharynx, and larynx), is caused by Corynebacterium diphtheriae. In comparison to L pneumophila and H influenzae, Corynebacterium diphtheria, is a also rod shaped but non motile like H influenza, and in contrast, is gram positive and non fastidious. Normally, streptococcus pneumoniae is a inhabitant of the human upper respiratory tract., but it causes infections like pneumonia, bacteremia, otitis media, meningitis, sinusitis, peritonitis and arthritis. Streptococcus pneumoniae cells are Gram-positive, coccus bacteria. Usually, they are seen as pairs of cocci (diplococci), but they may also occur singly and in short chains.They can be aerobic or anaerobic and are often capsulate. Streptococcus pneumoniae is known in medical microbiology as the pneumococcus, referring to its morphology and its consistent involvement in pneumococcal pneumonia. Streptococcus pneumonia caused pneumonia can be divided into two forms, bronchial pneumonia (100%), most prevalent in infants, young children and aged adults and and lobar pneumonia (80%), which is common in younger adults Streptococcus pyogene, a gram positive cocci, non motile and non spore forming bacteria, causes streptococcal pharyngitis, which is popularly known as strep throat. Strep throat is characterized by a painful, red throat with white patches on tonsils, and is accompanied by swollen lymph nodes, fever, and headache. Streptococcus pyogenes is considered to be an opportunistic pathogen. This is so because it is part of the normal flora of the respiratory tract in many people, not causing any complications until the persons natural defenses become immunocompromised. Mycobacteruim tuberculosis, are rods, gram positive, acid fast and obligate aerobic bacteria. They cause the disease Tuberculosis (TB) whose importance has been compounded by the emergence of AIDS and the appearance of multiple drug-resistant (MDR) strains of M. Tuberculosis. TB most commonly affects the lungs but also can involve almost any organ of the body. There is a vaccine against Tb called Bacille Calmette Guà ©rin, also known as BCG, which is a vaccine given throughout many parts of the world. TB is one of the most serious infectious disease of the resource poor world. It is persistent wherever poverty, malnutrition and poor housing prevail. It affects the apparently healthy as well as being a serious disease of the immunocompromised, as it is particularly with patients with HIV/AIDS. TB is primarily a disease of the lungs, but may spread to other sites Bordetella pertussis, the small gram negative coccobacilli, are slow growing and fastidious bacteria. They cause a disease called whooping cough, whose name is because of the characteristic sound produced when affected individuals attempt to inhale; theà whoopà originates from the inflammation and swelling of the laryngeal structures that vibrate when there is a rapid inflow of air during inspiration. Wooping cough is characterised in three main phases. Theà first stageà of whooping cough is known as the catarrhal stage, in which symtoms are runny nose, sneezing, low-grade fever, mild, occasionalà cough, similar to the common cold. The cough gradually becomes more severe, and after one to two weeks, the second stage begins. It is during theà second stageà (the paroxysmal stage) that the coughing is most severe. A series of closely spaced coughs occurs, followed by a `whoop` as air is inhaled. Vomitting may be stimulated by the coughing process. Coughing can occasionally be so severe as to rupture blood vessels in the eye or meninges. Theà third stageà of whooping cough is the recovery or convalescent stage, where there is a marked decrease in vomiting and paroxysms becomes less frequent and the child sleeps better. And towards the end of this phase, the coughing stops. Whooping cough commonly affects infants and young children but can be prevented by immunization with pertussis vaccine Transmission L. pneumophila is not acquired through a person to a person transmission. The bacteria, thus the disease is acquired by inhalation of contaminated water from showers, Respiratory therapy equipment,air conditioning systems as well as cooling towers. And the bacteria will usually cause respiratory disease in humans after a susceptible host inhales aerosolized water containing the bacteria or aspirates water containing the bacteria. Legionnaires disease is one of the causes of atypical pneumonia and even after inhalation of the bacteria, disease is not obvious. There are therefore,e risk factors which are associated with one getting Legionnaires disease. These are, cancer, usually pulmonary or hematological malignancy, Smoking, Surgery,Diabetes, HIV/AIDS ,Chronic cardiopulmonary disease, Advanced age and Alcohol abuse Haemophilus influenza is a normal habitat of the upper respiratory tract of humans and other animals. The infective bacteria are transmitted from person to person, by air borne route. This is typically through sneezing, coughing, or touching. Corynebacterium diphtheria is a normal habitat of human nasopharynx and occasionally, the skin. Therefore, the disease Diphtheri,a is transmitted from the infected to others via airborne respiratory droplets or by direct contact with nasopharyngeal secretions or skin lesions. Quite, rarely, it can be spread by objects which are contaminated by an infected person. The spread of diphtheria is increased by overcrowding and poor living conditions. Raw milk has served as a vehicle. Infected individuals may develop symptoms of diphtheria, or they may become carriers of the bacteria with no symptoms (asymptomatic carriers). These asymptomatic carriers can serve as reservoirs for active infection and may transmit the disease to other individuals Streptococcus pneumonia is a normal habitat of the human respiratory tract. Therefore, the spread of the bacteria is primarily via droplet spread or aerosol or through contact with nasal secretions of the infected person. It is therefore. a transmission of person to person. Streptococcus pyogenes is a normal habitat of the human upper respiratory tract as well as the skin. The respiratory disease caused by these bacteria, Streptococcal pharyngitis is acquired by inhaling aerosols emitted by infected individuals. Spread is therefore by air-borne droplets, through sneezing and coughing and by contact. M. tuberculosis has the ability to survive in the environment due to the waxy outer coat and this is what aids the transmission of bacteria through air borne droplet spread because they can survive for long periods of time in air and house dust. Therefore, a person can become infected with M. tuberculosis when they inhale minute particles of infected sputum from the air. TB is acquired by inhalation of Mycobacterium tuberculosis in aerosols and dust. Air-borne transmission of TB is every effective because infected people release enormous numbers of mycobacterial into the environment, when they cough, sneeze, shout, or spit. In the transmission of TB, social and environmental factors as well as genetic predisposition have a role to play. B. pertussis causes whooping cough, which is a highly contagious disease and is spread among people by direct contact with the nose or mouth fluids from of infected people. People may contaminate their hands with respiratory secretions from an infected person and then touch their own mouth or nose. Another way is that small bacteria-containing droplets of mucus from the nose or lungs enter the air during a cough or sneeze and people can become infected by breathing in these drops. And in vaccinated populations, B.pertussis is brought home by an older person, like even a parent, then spread to the vulnerable population of children. Pathogenesis Once L. pneumophila bacterium is in inhaled, infection will begin. The bacteria virulence factors are unclear, but the bacteria have a way of surviving in the alveolar macrophages. The infection though, will be obvious, if the person has other predisposing risk factors like smoking, cancer, HIV/AIDS, surgery, advanced age, alcohol abuse and diabetes. About 2-9 days after inhaling the bacteria, symptoms will involve headaches, fever chills and a cough which is nonproductive but may become productive as disease progresses. There will also be other symptoms involving the gastrointestinal tract like vomiting, nausea and diarrhea Arthralgias and myalgias are the musculoskeletal symptoms often experienced. And when the L.pneumophila bacteria get to the alveoli, they are attacked by the alveolar macrophages. These alveolar macrophages, will take the bacteria into the food vacuole inside the cell. Most often, the infection will progress because instead of the bacteria being destroyed by the macrophages, the bacteria will instead stop the fusion of the lysosome and monocyte. This will result in the bacteria to multiply inside the macrophage, and they eventually lyse the cell as well as infect other cells. Disease will progress from here. H. influenza interfers with the local expression of the immune response in tissues. Therefore, it does not interfere with the development of an immune response, but will just actively interfere with its expression in tissues. This bacteria liberates a protease that cleaves human IgA antibogy. H. influenza is a resident or invades mucosa where IgA antibodies operate. H. influenzaeà has a polysaccharide capsule which is an important virulence factor. This is because the capsule allows the bacteria to resist digestion by phagocytosis. These capsules also protect the bacteria when taken up by the lung macrophages. Diphtheria, the disease is due to production of diphtheria toxin which is controlled by the tax gene, which is integrated into the bacterial chromosome on a lysogenic phage. The toxin`s mode of action is the blocking of protein synthesis in the host epithelial cells by inactivating the elongation factor. The signs and symptoms of respiratory diphtheria, which begin after a 2-5 days incubation period, are because of the bacteriums ability to cause a localized inflammatory reaction of the cells lining the upper respiratory tract. The initial symptoms will be moderate fever, malaise, hoarseness, difficulty in breathing and swallowing and a sore throat. Later the complications may be cardiac, neurologic, infectious, like lung, bone and blood infection and death. So, when respiratory diphtheria progresses, the infected individual may also develop a gray membrane (pseudomembrane) which will form over the lining tissues of the tonsils and/or nasopharynx. In severe disease, patients may also develop neck swelling and enlarged neck lymph nodes. The extension of the pseudomembrane into the larynx and trachea can eventually lead to obstruction of the airway with subsequent suffocation and death. Immunization is the best prevention against diphtheria. The clinical symptoms of S. pneumoniae caused pneumonia include sudden onset of high fever, chest pains, dyspnea and a cough productiveof bloody sputum. In adults though, on set may be less sudden with shortness of breath, fever and altered mental status being the first symptoms of pneumonia. In young children and infants, vomiting, convultions and fever may be the first signs. Pnuemococcal pneumonia is one of the important causes of death in the elderly and infants. And the ones at high risk are those with chronic conditions and with immune deficiencies. Other complications that can arise from infection can be acute respiratory distress syndrome, septic shock, and empyema. S pneumoniae is a typical extracellular bacterial pathogen, which has a capsule that protects it from phagocytosis. Therefore, its pathogenicity requires adherence to host cells as well as the ability to replicate evade phagocytosis. It is in this effect that the organism must then gain access to areas where it can manifest infection, either through direct extension or lymphatic or hematogenous spread. Through direct extension, organisms may gain access to areas of the upper and/or lower respiratory tracts (sinuses, bronchi, eustachian tubes) after the colonization. Normally, in a healthy host, anatomic and ciliary clearance mechanisms will prevent clinical infection. But, clearance may be reduced by chronic (bronchitis, smoking, allergies,) or acute (viral infection, allergies) factors, which can lead to infection. Alternatively, by hematogenous spread and after mucosal invasion, pneumococci may reach normally sterile areas, such as the blood, peritoneum, cerebrospinal fluid, or joint fluid Symptoms of strep throat are sore throat, high fever, coughing, swollen lymph nodes and tonsils and a fiery red appearance to pharyngeal tissues which is du to tissue erosion. The M protein enhances the pathogenicity of S. Pyogenes. This protein, which is anchored in the cell wall and cell membrane, encourages adherence to the pharyngeal tissue and retards phagocytosis of the bacteria by the phagocytic cells of the host. Host immunity to Streptococcus pyogenes results from the development of antibodies specific to M protein. Over 80 specific types of M protein have been identified and complete immunity to streptococcal disease requires that a person produce antibodies against all 80 types. In developing countries, TB is a major cause of death and disability. In all cases, the disease begins with exposure to an infectious human source, thereafter, subsequent infection usually goes without notice. The first stage which is called primary infection causes no outward clinical manifestations. In this stage, the bacteria are engulfed by the alveolar macrophages where they can both survive and multiply. Primary TB is often mild and asymptomatic and often in 90% of cases, it does not proceed further. But clinical manifestations develop in the remaining 10% leading to active tuberculosis. and it may take several months from the time the infection initially gets into the lungs until the symptoms develop. In active TB infection, the usual symptoms are a generalized tiredness orà fever, weight loss, weakness, and night sweats. And if the infection in the lung worsens then, chest pain, coughing,à coughing up of sputum and/or blood, and shortness of breath may be experienced. In the event that there is spread of infection beyond the lungs, the symptoms will depend upon the organs involved. M. tuberculosis is an intracellular pathogen, meaning, it is capable of surviving within macrophages. It is capable of surviving intra-cellularly through the inhibition of phagosome-lysosome fusion. Cell mediated immunity alos comes into effect, which causes infiltration of macrophages and lymphocytes with development of granulomas (tubercles).. Much of the pathology of TB is due to host immune responsiveness rather than to direct bacterial toxicity. And at times, the bodys immune system becomes weakened, and the TB bacteria break through the scar tissue and can cause active disease, referred to as reactivation tuberculosis or secondary TB. Like the immune system can be weakened by old age, chemotherapy, HIV/AIDS and certain other medications. B.pertussis usually colonizes the ciliated respiratory epithelium of the trachea-bronchial tract. This colonization prevents the cilia from eliminating materials from the respiratory tract and it is this accumulation of materials which stimulates the coughing. It has been seen that capsulation of the bacteria canvplay a role in the successful colonization. A variety of virulence factors of B. pertussis have been demonstrated which are: The Pertussis toxin known for causing death Adenylate cyclise toxin play a role in inhibiting s the defensive functions of neutrophils Tracheal cytotoxin which kills the tracheal epithelial cells and causes local inflammation And the Endotoxin Pathogenesis of B. pertussis is that it colonizes an area which is normally bacteria-free i.e the respiratory epithelium and then disrupts or destroy the first line defense mechanism i.e the cilia The infection is promoted by the bacterium.. Laboratory Diagnosis Legionella pneumophila can be diagnosed in the lab by the following ways, Culture: The specimens are bronchial washings and bronchoalvealor lavage which are better collected before commencement of antibiotic therapy. Legionellae are fastidious organisms requiring cysteine and other essential growth promoting factors for their successful isolation and need 48 hours incubation before growth is visible for up to five days or more. A negative culture is not an obvious exclusion the diagnosis of legionellosis. Serological test Ideally, paired sera collected as soon as possible after the onset of illness and 3 to 6 weeks later should be tested. Direct Fluorescent antibody (DFA) Legionellae can be detected in respiratory secretions by DFA for several days after the start of antimicrobial therapy. DFA staining has also been used for serologic identification of Legionella isolates. Urine Antigen Detection Urinary antigen testing has helped in the recognition of outbreaks of Legionnaires disease allowing for a rapid public health response. Also urine antigen helps make an early diagnosis thus the initiation of appropriate antibiotic therapy. immunochromatographic (ICT) membrane assay. This is a very simple test, not needing special laboratory equipment, giving results within 15 min. Nucleic acid based tests Poymerase Chain Reaction (PCR) tests that have been developed for legionellae Diagnosis of H. influenzae pneumonia is made by successfully culturing, isolation and identification of the bacteria. Identifying H. influenzae needs a sample to be taken from infected tissue and be confirmed by laboratory tests. The specimen is usually grown on culture with the following conditions: On chocolate blood agar ( which is prepared by adding blood to an agar base at 80oC) Incubated at 35-37oCà with optimal pH of 7.6.à under aerobic conditions or under slight CO2à tension (5% CO2 The diagnosis of diphtheria is confirmed by isolation of the bacteriumà Corynebacterium diphtheriae. Specimens are taken from the nose and throat in any individual suspected of having diphtheria, as well as their close contacts. For culture, Corynebacterium diphtheriae, can be isolated (and diphtheria can be diagnosed) using the following conditions: Using blood culture-identification is aided by a selective medium on which characteristic black colonies form within 48 hrs at 35 degrees celcius . Biochemically, it is catalase positive and reduces nitrate. The Elek test is used to demonstrate toxin production of the bacteria. Polymerase Chain Reaction (PCR) is also used for the identification of the toxin gene Streptococcus pneumoniae can be isolated and identified using culture and biochemical tests. The specimen is usually grown on culture with the following conditions: By use of at 5% blood agar which will grow colonies that characteristically produce a zone of alpha (green) hemolysis, and this differentiates S. pneumoniae from the group A (beta hemolytic) streptococcus, Biochemically, S. pneumoniae is catalase negative and is distinguished from other streptococci by inulin fermentation, optochin sensitivity and bile test. PCR is also available for diagnosis as well as for screening for S.pnumoniae by using respiratory samples or feces When cultured on blood agar, they are alpha hemolytic. Individual cells are between 0.5 and 1.25 micrometers in diameter. They do not form spores, and they are nonmotile. Like other streptococci, they lack catalase and ferment glucose to lactic acid. Unlike other streptococci, they do not display an M protein, they hydrolyze inulin, and their cell wall composition is characteristic both in terms of their peptidoglycan and their teichoic acid S.pyogenes caused Strep throat can be diagnosed through a throat culture or a rapid strep test. The throat culture will be grown on an enriched medium containing blood. S. pyogenes is fermentative, is a facultative anaerobe and is a catalase-negative TB can be diagnosed by a skin test for delayed hypersensitivity with tuberculin. A positive test does not necessarily indicate active disease; merely exposure to the organism Staining and microscopic exam of sputum specimens for the presence of acid-fast bacteria is a rapid test for tuberculosis. When cultured, M. tuberculosis grows very slowly, meaning culture results may delay commencing of treatment for the patient. Culture also requires the use of complex media. Polymerase Chain Reaction (PCR) can also be used to diagnose TB. This test detects the genetic material of the bacteria, it is extremely sensitive (it detects minute amounts of the bacteria) as well as specific (it detects only the TB bacteria). Results are usually ready within a few days. Culture of the bacteriumà Bordetella pertussisà from nasal secretions can establish the diagnosis of whooping cough. Since there are difficulties in obtaining the adequate sample, swabs should be inoculated directly onto media at the patients` bedside. It is better to get both post and peri nasal swabs. B. pertussis fails to grow on routine blood agar and only requires enriched medium. Therefore, special media are used for isolation of B. pertussis, and these are Bordet Gengou medium and Lacey`s medium and it needs 3-7 days incubation in moist atmosphere. B.pertussis is then identified on colony appearance basis using the proper medium as well as agglutination tests. Polymerase Chain Reaction (PCR) has been used to successfully identify the bacterium and diagnose whooping cough. This test can identify genetic material from the bacterium in nasal secretions
Wednesday, October 2, 2019
Importance of Money in Midnight in the Garden of Good and Evil Essay
Importance of Money in Midnight in the Garden of Good and Evilà à à Inherited money is held in much higher esteem than earned money in Savannah, Georgia. This is a theme seen throughout Midnight in the Garden of Good and Evil, John Berendt's non-fictional account of life in Savannah. Characters such as Jim Williams, who worked for their money and brought themselves up the social ladder, are seen as being beneath those who inherited their money, such as Lee Adler. The old wealth tend to look down on anyone who wasn't born with their money. Their views of just about everything, including laws and punishments, differ depending on whether the person in question is of wealth due to blood or sweat. While Savannah is a town full of rich people, there isn't a whole lot of earned wealth. Most of Savannah's wealthy people have been rich for generations. Among the few exceptions is Jim Williams. He was born in Gordon, Georgia, a small town near Macon. "My father was a barber, and my mother worked as a secretary for the [town's chalk] mine. My money - what there is of it - is about eleven years old," says Williams (Berendt 4). Jim Williams is an oddity in Savannah. This "socially prominent antiques dealer" (Bellafante 79) is arrogant and pompous, but unlike those who are this way because they believe they were born with the right to be so, he is this way because he knows he has earned the right. It is because of this, though, that he is not truly accepted by his neighbors. For instance, there is the Oglethorpe Club, one of the highest class social clubs, even by Savannah standards. It would make sense for one of the richest aristocrats to be a premier member of the club. This is not the case, however. According to Berendt, bachelo... ... greatly upset those who hadn't had their turn. Appropriately enough, it seemed to Williams at least, it was Adler who prodded the district attorney to charge Williams with murder rather than a lesser crime. John Berendt's Midnight in the Garden of Good and Evil is a non-fictional account of the aristocratic lifestyle of Savannah, Georgia. The book examines many aspects of life in Savannah, as well as the mind sets of its people. One of these mind sets is the conflict between "old money" and "new money." People who have always had money seem to think that they are of a higher class than those who have had to work for it. Lee Adler and Jim Williams are two of the combatants in this ongoing war. Adler fights for the side of inherited money, Williams for earned. The problem for Williams is that the inherited side seems to control all the cards, even those of the law. Importance of Money in Midnight in the Garden of Good and Evil Essay Importance of Money in Midnight in the Garden of Good and Evilà à à Inherited money is held in much higher esteem than earned money in Savannah, Georgia. This is a theme seen throughout Midnight in the Garden of Good and Evil, John Berendt's non-fictional account of life in Savannah. Characters such as Jim Williams, who worked for their money and brought themselves up the social ladder, are seen as being beneath those who inherited their money, such as Lee Adler. The old wealth tend to look down on anyone who wasn't born with their money. Their views of just about everything, including laws and punishments, differ depending on whether the person in question is of wealth due to blood or sweat. While Savannah is a town full of rich people, there isn't a whole lot of earned wealth. Most of Savannah's wealthy people have been rich for generations. Among the few exceptions is Jim Williams. He was born in Gordon, Georgia, a small town near Macon. "My father was a barber, and my mother worked as a secretary for the [town's chalk] mine. My money - what there is of it - is about eleven years old," says Williams (Berendt 4). Jim Williams is an oddity in Savannah. This "socially prominent antiques dealer" (Bellafante 79) is arrogant and pompous, but unlike those who are this way because they believe they were born with the right to be so, he is this way because he knows he has earned the right. It is because of this, though, that he is not truly accepted by his neighbors. For instance, there is the Oglethorpe Club, one of the highest class social clubs, even by Savannah standards. It would make sense for one of the richest aristocrats to be a premier member of the club. This is not the case, however. According to Berendt, bachelo... ... greatly upset those who hadn't had their turn. Appropriately enough, it seemed to Williams at least, it was Adler who prodded the district attorney to charge Williams with murder rather than a lesser crime. John Berendt's Midnight in the Garden of Good and Evil is a non-fictional account of the aristocratic lifestyle of Savannah, Georgia. The book examines many aspects of life in Savannah, as well as the mind sets of its people. One of these mind sets is the conflict between "old money" and "new money." People who have always had money seem to think that they are of a higher class than those who have had to work for it. Lee Adler and Jim Williams are two of the combatants in this ongoing war. Adler fights for the side of inherited money, Williams for earned. The problem for Williams is that the inherited side seems to control all the cards, even those of the law.
Hawthornes Hierarchy of Sin in The Scarlet Letter Essay -- Scarlet Le
Hawthorne's Hierarchy of Sin in The Scarlet Letterà à à à à Throughout the novel The Scarlet Letter, Nathaniel Hawthorne focuses on the struggle of Hester Prynne, a woman who is forced to deal with the strict Puritan punishment for the adulterous birth of her child, Pearl.à Yet, the very Puritan values that bring Hester public ignominy help to lift her to a position of respect in the community.à Although Hawthorne does not condone Hester's sin, he takes pains to show that her sin is minimal in comparison to those of her weak lover, Arthur Dimmesdale, and of her vengeful husband, Roger Chillingworth. à à Hester finds solace in the moral teachings of her religion and in acts of repentance, which help her deal with the struggles resulting from her sin.à Although she no longer practices her faith openly after her public disgrace, she still has deep ties to her God and religion.à She often prays for Pearl in hopes that her child's wild character will be calmed with time.à Hester accepts her punishment readily, elaborately embroidering the scarlet "A" she is forced to wear on her breast and dressing Pearl in scarlet.à She continues to wear the symbol of her sin long after the community declares her repented due to her commendable record of community service, showing everyone that she has nothing to hide.à Indeed, Hester's salvation lies in the truth:à "In all things else, I have striven to be true!à Truth was the one virtue which I might have held fast, and did hold fast, through all extremity. à . . . A lie is never good, even though death threaten on the other side!" (200).à Hester finds comfort in prayer and repentance, which help to make her strong:à "Shame, Despair, Solitude!à These had been her teachers- s... ...esdale.à For his sins Chillingworth suffers a horrible fate:à "All his strength and energy-all his vital and intellectual force-seemed at once to desert him; insomuch that he positively withered up, shriveled away, and almost vanished from mortal site. . ." (268).à He dies very shortly after Dimmesdale. à à Although it appears at first glance that Hester is Hawthorne's focus in The Scarlet Letter, a closer examination reveals that the novel revolves around the struggles of a weak lover and a jealous husband.à Indeed, Hawthorne shows that Hester, who readily faces her problems, grows stronger and gains the respect of her community, whereas both Dimmesdale and Chillingworth, who are consumed by fear and hate respectively, bring about their own demise. à Works Cited Hawthorne, Nathaniel.à The Scarlet Letter.à New York: Dodd, Mead & Co., 1948.
Tuesday, October 1, 2019
Information to commit a crime Essay
The article from The Mail on Sunday spreads over 2/3s of a page. It is at first glance more interesting than the previous article because it contains a large color picture of Lord Archer and his wife, and a smaller picture of the book he has recently published. Articles with pictures beside them seize the readerââ¬â¢s attention. The caption under the picture of Archer and his wife reads ââ¬Ëinside job:ââ¬â¢ which suggests a crime has been committed from inside prison. ââ¬ËInside jobââ¬â¢ is a word used to refer to those who use their access to privileged information to commit a crime. It is an exaggerated and dramatic term to use, which will catch the readerââ¬â¢s interest. ââ¬ËArcher could pocket a fortune from his prison diary, left, which could ease his and wife Maryââ¬â¢s cash flow problemsââ¬â¢ This sentence is intended to be humorous because it is sarcastic. The lord and lady are not expected to have any money troubles or ââ¬Ëcash flow problemsââ¬â¢. Humor is a method used by journalists to incite their readers. Also, here is introduced a motive for releasing the book that was not mentioned in the other article. However the article does not hold substantial evidence that this is true, and not just a conclusion drawn by the reporter for the purpose of obtaining public interest. The article says that this had been said by ââ¬Ësources close to the familyââ¬â¢. Nevertheless it does go on to say that Archer recently paid out 2. 7 million to Express Newspapers. The Mail on Sunday article is similarly set out in columns. Unlike The Sunday Telegraph this article contains larger font for the first two paragraphs of the article. This is done because it contains the basis of the story and larger font stands out more. There is one enlarged quote, which reads ââ¬ËHe simply put his memoirs in the postââ¬â¢. The reporter chose to enlarge this because it will surprise the readers. It is a controversial point: should Archer really have just been allowed to post his memoirs. The article uses language such as ââ¬Ëfar from smuggling the manuscript out ââ¬Ë which suggests this is what would have been expected. The article goes on to explain that prison authorities can check prisoners outgoing post and that they could have censored Archerââ¬â¢s book. This leaves the reader wondering why they allowed Archerââ¬â¢s book to get out. Could it be because he is a Lord and has high social status than the average prisoner? I think that is what the article is suggesting throughout. It does this because it wants to raise a point, make the readers think and get their attention. The language in this article uses more adjectives than the Sunday Telegraph article, examples of this are: Calls were made for Archer to be dealt with ââ¬Ëharshlyââ¬â¢. A spokesman ââ¬Ëcriticizedââ¬â¢ the prison service. This has the effect of persuading to the reader to agree with the reporterââ¬â¢s point of view. Unlike the Sunday Telegraph article it refuses to sit on the fence. Both the articles are similar to each other in some of the ways they were written. For instance it is written like a story with intervening quotes and opinions from different people. Frances Crook says ââ¬Ëanyone should have the right to free speech and free expressionââ¬â¢. The article also stops to explain facts to the reader such as ââ¬Ëletters or phone calls to or from the prison can be readââ¬â¢. The Mail on Sunday talks about many more different aspects relating to the story than the Sunday telegraph which chooses to stick to the main story. The Mail on Sunday article speaks of the ââ¬Ëcash flow problemââ¬â¢. It explains what else has happened to Archer whilst he has been in prison, ââ¬Ëused a weekend home leave to attend a champagne partyââ¬â¢ and ââ¬Ëlavish lunches with prison staff ââ¬Ë. The word ââ¬Ëlavishââ¬â¢ suggests to the reader that Archer is having an easy time, living the life of a high society, rich man. It is said because the reporter feels that Archer should not be treated as well as he is, because he is a criminal. It goes on to explain that these ââ¬Ëbreaches of prison rulesââ¬â¢ has meant he has been transferred. The first paragraph of this article says Archer is ââ¬Ëexpected to escape any severe punishmentââ¬â¢ for publishing his Prison Diaries. It also states that the diary is likely to net him at least 300,000. The word ââ¬Ëescapeââ¬â¢ suggests to the reader that Archer deserves a punishment and is getting out of it. The 300,000 is also a lot less than the 500,000 the Sunday Telegraph said Archer had gained. The effect of money written of in the first paragraph is also make the reader interested and angry that Archer has received so much money but will not be punished for his crime. The title stating that the punishment for Archerââ¬â¢s crime is to have his TV removed is not completely accurate. A prison service insider as one of a number of possible punishments mentioned it. The article picked up on this and enlarged its importance to capture readerââ¬â¢s attention because it sounds like a stupid and unfair punishment. The article also mentions that ââ¬Ëunder Prison Rule 55, Archer could have seven weeks added to his sentenceââ¬â¢. However this is still a lot less than the ââ¬Ëextra yearââ¬â¢ mentioned in the other article. The two Newspaper articles were very similar in many ways because they were of the same type of media. I found the main differences between them were the main facts of their stories, the punishments disagreed with each other. They both used different techniques for get the readers attention. The purpose of this was to capture and maintain an interest in the article. The overall purpose is to sell newspapers, and make money. The Sunday Telegraph is known to be a more trustworthy newspaper than tabloids such as the Mail on Sunday. The article in the Sunday Telegraph was a straightforward news event and it had no signs of being biased. All the facts were presented The Mail on Sunday appealed more to peopleââ¬â¢s need for gossip and scandal, it tried to make the reader feel annoyed and shocked. This article was better at catching the readerââ¬â¢s eye because of the layout and bright pictures. I think the Mail on Sunday also did a better job of maintaining the readerââ¬â¢s interest because most people like to read about the more scandalous side of stories and it is more interesting when an article sways your emotions. The Sunday Telegraph, can be trusted to give a relatively non-biased true account but it is less interesting to read. The language in both articles was very similar; both used simple, factual writing backed up with quotes.
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